Fig. 4

RCT Average spontaneous pain reduction at individual level, and in discrete improvement intervals. A Percentage reduction in the average NRS pain intensity from baseline to end of treatment. Negative scores denote worsening; B Percentage of patients achieving step-reductions in their average NRS scores from baseline to the end of treatment, where MCID denotes minimal clinical important difference of equal to 2; n = 31 active, n = 34 sham