Fig. 1
From: Circular RNA circPIP5K1A contributes to cancer stemness of osteosarcoma by miR-515-5p/YAP axis
The expression of circPIP5K1A is enhanced in clinical osteosarcoma tissues and contributes to osteosarcoma cell proliferation in vitro. A CircPIP5K1A expression was determined by qPCR in clinical osteosarcoma tissues (n = 45) and adjacent normal tissues (n = 45). B CircPIP5K1A expression was assessed by qPCR in MG63, 143B, U2OS and Saos2 osteosarcoma cell lines. C–F MG63 and 143B cells were transfected with circPIP5K1A siRNA. C CircPIP5K1A expression was analyzed by qPCR. D Cell viability was examined by MTT analysis. E, F Cell apoptosis was tested by Annexin V-FITC/PI detection kit. Mean ± SD (**P < 0.01)