Fig. 2

Confocal images of p24 in CD45+ lymphocytes or CD4+ T cells from hu-mouse tissues. Shown are a donor PBMC infected in vitro (A) and HIV(+) CD45+ (B), HIV(−) CD45+ (C), HIV(+) CD4+ (D), or HIV(−) CD4+ (E) lymphocytes or T cells in mouse liver, lymph node, and spleen from infected or uninfected hu-mice. Representative tissue sections were analysed by α-p24 mAb in red and human α-CD45 or -CD4 in green among the indicated groups of mice. White arrows indicate cells expressing p24 (A, B, and D). The bar size is 5 µm for PBMCs in panel A and 10 µm for tissue sample cells in panels B–E