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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Cytotoxic lymphocytes-related gene ITK from a systematic CRISPR screen could predict prognosis of ovarian cancer patients with distant metastasis

Fig. 1

Establishment of orthotopic transplant tumor model in NOD-SCID mice and high-throughput screening of genes associated with metastasis using CRISPR/Cas9 library, A Flow chart of ovarian cancer orthotopic mouse model construction. B In vivo imaging of CRISPR-Lib and CRISPR-Vec at different stage, n = 18. C Photo Flux change of CRISPR-Lib and CRISPR-Vec,** p < 0.01, *** p < 0.001. D Volcano plot of metastasis-related candidate genes. Red dots represent inhibit genes in ovarian tumor metastasis model

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