Fig. 2

Discovery of circRNAs specifically expressed in GSCs and construction of a GSC-specifically expressed circRNA-miRNA regulatory network. A, B Abnormal circRNA expression in GSC23 was demonstrated in the heat map and volcano plot. C, D The dysregulated miRNA expression profile in glioma cells is demonstrated in the heat map and volcano plot. E We screened out 11 target miRNAs. F Cytoscape 3.8.2 was used to draw the GSC23-highly expressed circRNA-miRNA regulatory networks