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Table 2 Comparison of patient conditions before and after therapy

From: Clinical outcomes and safety of polymyxin B in the treatment of carbapenem-resistant Gram-negative bacterial infections: a real-world multicenter study

Parameter Baseline After therapy P
Heart rate, bpm, mean ± SD 92.02 ± 21.55 97.36 ± 20.35 0.895
Temperature, ℃, median (IQR) 38 (37.1, 38.7) 37.1 (36.7, 37.6) < 0.001
WBC, × 109/L, median (IQR) 14.13 (10.08, 20.02) 9.28 (7.02, 13.40) < 0.001
PLT, × 109/L, mean ± SD 111.71 ± 97.68 190.95 ± 162.99 < 0.001
CRP, ug/l, median (IQR) 103.55 (56.96, 180.83) 47.6 (13.08, 102.58) < 0.001
PCT, ng/ml, median (IQR) 3.89 (1.09, 11.43) 1.695 (0.46, 5.41) < 0.001
SOFA, mean ± SD 7.74 ± 4.13 7.32 ± 4.41 0.282
APACHE II, mean ± SD 17.75 ± 7.69 15.98 ± 7.95 0.007
Mechanical ventilation, n (%) 51 26 < 0.001
Septic shock, n (%) 49 26 < 0.001
  1. Categorical variables are presented as numbers (%), and continuous variables are presented as mean ± SD or interquartile ranges [IQR]
  2. WBC: white blood cell; CRP; C-reactive protein; PLT: platelet count; PCT: procalcitonin; SOFA: Sequential Organ Failure Assessment; APACHE II: Acute Physiology and Chronic Health Evaluation II; SD: standard deviation