Fig. 4

TC17 ovarian morphology demonstrates altered folliculogenesis. A General scheme of a long-term study in TC17. After Dox treatment (8 weeks), CTRL and TC17 mice were sacrificed, and ovaries were collected (N = 6). B Histological analysis of ovaries stained with H&E at the end of the treatment course. Top panels, representative images. Bottom panels, insets of images in top panels. C Body mass (grams, top panel) and ovarian weight (mg, bottom panel) in CTRL and TC17 mice (N = 6), means ± s.e.m. Data were analyzed using the two-tailed Mann–Whitney test (**p < 0.01)