Useful functionality | Harmful functionality |
---|---|
1. Progenitor function for podocytes | 1. Abnormal proliferation leads to crescentic glomerulonephritis and collapsing glomerulopathy |
2. Intracellular tight junctions restrict glomerular filtrate to urinary space | 2. Participate in glomerular scarring |
3. Possible synthesis and repair of Bowman’s basement membrane |  |