Fig. 4

FBXO43 knockdown inhibited the migration and invasion of MDA-MB-231 cells. A, B Scratch wound healing assay. C, D Transwell migration assay (without ECM). E, F Transwell invasion assay (with ECM). All experiments were performed at least three times. All cell images were obtained under a microscope at 100 × magnification. ECM extracellular matrix, NC negative control, KD FBXO43 knockdown. *P < 0.05, **P < 0.01, ***P < 0.001