Fig. 4

MiR-144-3p directly targets 3’-UTR of GLI2 mRNA. a The potential miR-144-3p binding sites in 3’-UTR of GLI2 mRNA predicted by TargetScan. b The sequence of the WT-GLI2 and MUT-GLI2 3’-UTR reporter plasmids. c The relative luciferase activity in HEK293T co-transfected with miR-144-3p mimics or negative control (NC) and WT-GLI2 or MUT-GLI2 reporter plasmid. (**p < 0.01, ns = no significance)