Table 3 Regional brain T2-relaxation values (mean ± SE, ms) of CF patients and control corrected for age and sex
From: Regional brain tissue changes in patients with cystic fibrosis
Brain areas | CF (n = 5) | Controls (n = 15) | p-values |
|---|---|---|---|
Mean ± SE (95% confidence interval) | Mean ± SE (95% confidence interval) | ||
L Prefr Cor | 139.5 ± 3.3 (132.6–146.4) | 162.5 ± 1.8 (158.7–166.3) |  < 0.001 |
R Prefr Cor | 162.6 ± 7.7 (146.2–179) | 199.2 ± 4.3 (190.2–208.3) | 0.001 |
L cerebellum | 123.6 ± 4.3 (114.5–132.6) | 149.3 ± 2.4 (144.3–154.3) |  < 0.001 |
R cerebellum | 123.3 ± 2.4 (118.1–128.4) | 136.0 ± 1.3 (133.1–138.8) |  < 0.001 |
L cerebellar tonsil | 126.9 ± 4.8 (116.6–137.1) | 160.8 ± 2.7 (155.2–166.5) |  < 0.001 |
R cerebellar tonsil | 127.5 ± 5.1 (116.7–138.3) | 159.1 ± 2.8 (153.1–165) |  < 0.001 |
R insula | 157.6 ± 5.5 (146–169.1) | 182.7 ± 3.0 (176.4–189.1) | 0.001 |
Brainstem | 138.1 ± 6.5 (124.4–151.8) | 168.2 ± 3.6 (160.6–175.7) | 0.001 |
L frontal Cor | 133.8 ± 3.3 (126.9–140.8) | 155.4 ± 1.8 (151.6–159.3) |  < 0.001 |
L parietal Cor | 152.4 ± 6.2 (139.2–165.6) | 182.6 ± 3.4 (175.3–189.8) | 0.001 |
R parietal Cor | 128.0 ± 4.6 (118.4–137.7) | 148.9 ± 2.5 (143.6–154.3) | 0.001 |
L Sup Temp Cor | 142.6 ± 4.8 (132.4–152.8) | 166.0 ± 2.7 (160.4–171.6) | 0.001 |
R Sup Temp Cor | 132.1 ± 3.2 (125.3–138.9) | 153.6 ± 1.8 (149.9–157.3) |  < 0.001 |
Corpus callosum | 121.3 ± 7.0 (106.4–136.2) | 154.5 ± 3.9 (146.3–162.8) | 0.001 |
L frontal WM | 119.7 ± 2.4 (114.7–124.7) | 134.2 ± 1.3 (131.5–137) |  < 0.001 |