Skip to main content

Table 3 Regional brain T2-relaxation values (mean ± SE, ms) of CF patients and control corrected for age and sex

From: Regional brain tissue changes in patients with cystic fibrosis

Brain areas CF (n = 5) Controls (n = 15) p-values
Mean ± SE (95% confidence interval) Mean ± SE (95% confidence interval)
L Prefr Cor 139.5 ± 3.3 (132.6–146.4) 162.5 ± 1.8 (158.7–166.3)  < 0.001
R Prefr Cor 162.6 ± 7.7 (146.2–179) 199.2 ± 4.3 (190.2–208.3) 0.001
L cerebellum 123.6 ± 4.3 (114.5–132.6) 149.3 ± 2.4 (144.3–154.3)  < 0.001
R cerebellum 123.3 ± 2.4 (118.1–128.4) 136.0 ± 1.3 (133.1–138.8)  < 0.001
L cerebellar tonsil 126.9 ± 4.8 (116.6–137.1) 160.8 ± 2.7 (155.2–166.5)  < 0.001
R cerebellar tonsil 127.5 ± 5.1 (116.7–138.3) 159.1 ± 2.8 (153.1–165)  < 0.001
R insula 157.6 ± 5.5 (146–169.1) 182.7 ± 3.0 (176.4–189.1) 0.001
Brainstem 138.1 ± 6.5 (124.4–151.8) 168.2 ± 3.6 (160.6–175.7) 0.001
L frontal Cor 133.8 ± 3.3 (126.9–140.8) 155.4 ± 1.8 (151.6–159.3)  < 0.001
L parietal Cor 152.4 ± 6.2 (139.2–165.6) 182.6 ± 3.4 (175.3–189.8) 0.001
R parietal Cor 128.0 ± 4.6 (118.4–137.7) 148.9 ± 2.5 (143.6–154.3) 0.001
L Sup Temp Cor 142.6 ± 4.8 (132.4–152.8) 166.0 ± 2.7 (160.4–171.6) 0.001
R Sup Temp Cor 132.1 ± 3.2 (125.3–138.9) 153.6 ± 1.8 (149.9–157.3)  < 0.001
Corpus callosum 121.3 ± 7.0 (106.4–136.2) 154.5 ± 3.9 (146.3–162.8) 0.001
L frontal WM 119.7 ± 2.4 (114.7–124.7) 134.2 ± 1.3 (131.5–137)  < 0.001
  1. CF cystic fibrosis, ms millisecond, SE standard error, L left, Prefr prefrontal, Cor cortex, R right, Sup superior, Temp temporal, WM white matter