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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: FAM83A promotes proliferation and metastasis via Wnt/β-catenin signaling in head neck squamous cell carcinoma

Fig. 6

FAM83A knockdown inhibits HNSCC growth and metastasis in nude mice. A The shFAM83A cells and control cells were subcutaneously injected into nude mice and general observation of tumor-bearing nude mice injected with cells. B Volumes of xenograft tumors in shNC and shFAM83A groups. C Tumor tissues in shNC and shFAM83A groups were weighed after 24 days. D Representative showings of tumors formed in the nude mice were diagnosed as HNSCC by HE staining (100 ×). E Representative photomicrographs of positive staining of FAM83A in shNC groups and negative staining of FAM83A in shFAM83A groups (100 ×). F, G Representative photographs of lung tissues in mice injected with shFAM83A cells and shNC cells and a summary of the number of lung metastatic nodules in shFAM83A and shNC groups. H HE staining of lung tissues in shNC and shFAM83A groups (H1, H3, 100 × ; H2, H4, 200 ×). Data represent the mean ± SD; *p < 0.05, **p < 0.01, ***p < 0.001

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