The role of PDGFRA as a therapeutic target in young colorectal cancer patients

Table 3 Downregulated oncogenes and tumor suppressor genes in young CRC

Gene	Fold change	q-value	Cancer associated	Full name
ZIC2	0.23	0.006	Oncogene	Zic family member 2
PPP1R1B	0.4	0.009	Suppressor gene	Protein phosphatase 1 regulatory inhibitor subunit 1B
NDRG2	0.43	0.001	Suppressor gene	NDRG family member 2 [Homo sapiens
FEZF1	0.44	0.039	Oncogene	FEZ family zinc finger 1 [Homo sapiens
NFIB	0.48	0.001	Oncogene	Nuclear factor I B
ZNF292	0.48	0.001	Suppressor gene	Zinc finger protein 292
PHLDA2	0.48	0.001	Suppressor gene	Pleckstrin homology like domain family A member 2
CEACAM6	0.49	0.021	Oncogene	Carcinoembryonic antigen related cell adhesion molecule 6
CEACAM1	0.49	0.001	Suppressor gene	Carcinoembryonic antigen related cell adhesion molecule 1

ISSN: 1479-5876