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Table 4 Comparison of iTTCA-RF and state-of-the-art predictors

From: iTTCA-RF: a random forest predictor for tumor T cell antigens

Tools Tenfold CV Independent test
BACC (%) AUC Sn (%) Sp (%) MCC BACC (%) AUC Sn (%) Sp (%) MCC
TTAgP1.0 63.68 0.838 70.85 56.50 0.838 68.68 0.747 78.69 58.67 0.379
iTTCA-Hybrid 78.83 0.840 85.53 72.13 0.588 70.73 0.783 82.79 58.67 0.428
iTTCA-RF 83.71 0.894 88.69 78.73 0.678 73.14 0.780 83.61 62.67 0.474
  1. The best performance value is highlighted in bold for clarification