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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: A novel immune subtype classification of ER-positive, PR-negative and HER2-negative breast cancer based on the genomic and transcriptomic landscape

Fig. 4

The genomic landscape of ER+/PR−/HER2− breast cancer. A Mutation profile is shown in column for each sample, including known cancer-related genes with top 20 mutation frequencies (top) and two recurrently homologous recombination gene in breast cancer (bottom). B The mutation frequencies of 10 common oncogenic pathways among clusters. C Heatmap of enrichment scores of 10 common oncogenic pathways among clusters. Asterisks indicate association with immune subtype (somatic mutation frequencies were tested using Fisher’s exact test. *P < 0.05, **P < 0.01, ***P < 0.001)

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