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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: A novel immune subtype classification of ER-positive, PR-negative and HER2-negative breast cancer based on the genomic and transcriptomic landscape

Fig. 3

Potential tumor immune escape mechanism of immune subtypes. A Expression of chemokines, IFNs, ILs and other cytokines and their receptors in each cluster. B Expression of MHC and immunomodulatory molecules for each cluster. Expression values are represented by z-score calculated across all ER+/PR−/HER2− breast tumors. C Mutation load and neoantigen load in each cluster. D Comparison of SCNV categories of CD274, PDCD1LG2, TNFRSF8 and TNFRSF9. E Correlation among immune infiltration, immunogenicity and expression of immune checkpoint molecules

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