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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: A novel immune subtype classification of ER-positive, PR-negative and HER2-negative breast cancer based on the genomic and transcriptomic landscape

Fig. 1

Immune subtypes and gene programmes defining ER+/PR−/HER2− breast cancer. A Unsupervised clustering analysis of microarray data identified five immune subtypes. B Heatmap of gene programmes significantly enriched in ER+/PR−/HER2− breast cancer. Scores for gene programmes (GP scores) were defined as the average expression level of all genes in a particular module. In the heatmap, colors represent mean GP scores of each cluster and black dots denote modules showing highest significance for an individual subtype. C, D Kaplan–Meier analysis of patient survival stratified by cluster: C OS; D BCSS

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