Fig. 8From: Overexpression of E3 ubiquitin ligase Cbl attenuates endothelial dysfunction in diabetes mellitus by inhibiting the JAK2/STAT4 signaling and Runx3-mediated H3K4me3The mechanistic diagram depicting the role of Cbl in HUVEC dysfunction in DM. Cbl blocked the JAK2/STAT4 pathway to downregulate the expression of Runx3 through H3K4me3 modification, thereby alleviating HUVEC dysfunction in DMBack to article page