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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: A new Mfn-2 related synthetic peptide promotes vascular smooth muscle cell apoptosis via regulating the mitochondrial apoptotic pathway by inhibiting Akt signaling

Fig. 5

Effects of MRSP on VSMC apoptosis after pretreatment with 740 Y-P or LY294002. A The apoptosis induced by MRSP of VSMCs pretreated with 740 Y-P was examined using TUNEL staining. B The influence of MRSP on Akt phosphorylation, Bcl-2, Bax expression and caspase-3 activation of VSMCs preincubated with 740 Y-P. C The apoptosis induced by MRSP of VSMCs pretreated with LY294002 was examined using TUNEL staining. D The influence of MRSP on Akt phosphorylation, Bcl-2, Bax expression and caspase-3 activation of VSMCs incubated with LY294002. n = 3 for this experiment. *p < 0.05, **p < 0.01

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Journal of Translational Medicine

ISSN: 1479-5876

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