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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Wnt pathway-related three-mRNA clinical outcome signature in bladder urothelial carcinoma: computational biology and experimental analyses

Fig. 1

A Forest plot of hazard ratios, showing the prognostic value of Wnt-associated genes; > 1 indicates a poor prognostic factor, and < 1 represents a favorable prognostic factor. Univariate analysis showed that the higher the expression level, the worse the outcome. B In TCGA, the expression levels of 34 Wnt- associated genes in BLCA WHO II and WHO III (*P < 0.05, **P < 0.01, ****P < 0.0001, NSP ≥ 0.05). C The expression level of the Wnt pathway in various samples. D The association between the module identification and the sample. Module feature relationship. The module name is showed on the left. The number in the first row of the square is the association coefficient with the Wnt signal group, displayed at the top of every row, and the p-value is printed under the correlation in parentheses. These lines are colored on basis of the association between the module and the Wnt signaling pathway: dark green means positive correlation, dark turquoise, and yellow-green means negative correlation. E The correlation between 34 essential genes and EMT. The blue box represents a negative association, a red box represents a positive association, and a growth of color shows a growth of the association coefficient

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