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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: A direct negative feedback loop of miR-4721/FOXA1/Nanog promotes nasopharyngeal cell stem cell enrichment and metastasis

Fig. 1

miR-4721 expression promotes stem cell enrichment in HONE1 and SUNE1 cells. A Analysis of SP cells from miR-4721-overexpressing or miR-4721-inhibited, and NC cells by flow cytometry. B ALDEFLUOR assay of Aldehyde dehydrogenase-positive cells of miR-4721-overexpressing or miR-4721-inhibited, and NC cells. C Representative images of the tumor sphere seeded at a density of 1000 cells/well for 7 days. D The nude mice were injected with 106, 5 × 105, 104, or 5 × 104 miR-4721-overexpressing cells or control cells on the left and right sides, respectively (n = 6). *P < 0.05

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