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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Bufalin suppresses tumour microenvironment-mediated angiogenesis by inhibiting the STAT3 signalling pathway

Fig. 6

Bufalin inhibits CRC cell metastasis via an antiangiogenic mechanism in vivo. a Scheme and schedule of imaging and treatments. b Tumour metastasis was visualized by an in vivo imaging system from day 7 to day 21. c Representative images of liver and H&E-stained liver tissue. d Tumour number and area in liver. e IHC analysis of CD31 in spleen and liver tissue. f VEGF expression level in serum. g Immunofluorescence analysis of CD31 and p-STAT3 in liver. **P < 0.01, ***P < 0.001. Data are shown as mean s.e.m. IHC, immunohistochemistry

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