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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: UBE2T promotes autophagy via the p53/AMPK/mTOR signaling pathway in lung adenocarcinoma

Fig. 6

The prognostic accuracy of the risk estimation model derived from UBE2T-related autophagy genes in the TCGA-LUAD cohort. To improve the prognostic accuracy of UBE2T, the LASSO regression model was used to establish the best risk signature from the UBE2T-correlated autophagy genes in the TCGA-LUAD cohort. A Lasso coefficients of UBE2T-related autophagy genes. B Determination of the optimal gene signature in the LASSO model. C 5-year ROC curves for indicated variables. The risk score has the highest AUC value of all individual risk factors. D Time-dependent ROC curves for the risk score. The cutoff value of the risk scores was evaluated by plotting ROC curves. E LUAD patients were divided into low- and high-risk groups by the cutoff value. The risk score is associated with patient OS. The Kaplan–Meier survival curves of OS time between low- and high-risk patients. F The distribution of the integrated score and survival status of the TCGA-LUAD patients

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