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Table 3 Univariate and multivariate Cox analyses of disease-free survival prediction, based on IRF scores calculated by cases from TCGA

From: Interferon regulatory factor family influences tumor immunity and prognosis of patients with colorectal cancer

Variable Univariate Cox analysis Multivariate Cox analysis
HR (95% CI) P value HR (95% CI) P value
Age (≥ 60 vs. < 60) 1.00 (0.60–1.69) 0.975 1.02 (0.59–1.78) 0.934
Gender (male vs. female) 1.15 (0.72–1.84) 0.567 0.75 (0.46–1.24) 0.263
T stage (T3 and T4 vs. T1 and T2) 8.40 (2.06–34.31) 0.003 3.41 (0.82–14.17) 0.091
N stage (N1 and N2 vs. N0) 4.77 (2.77–8.24)  < 0.001 0.74 (0.28–1.96) 0.547
M stage (M1 and MX vs. M0) 5.57 (3.45–8.99)  < 0.001 2.99 (1.72–5.18) 0.001
Stage (III + IV vs. I + II) 6.52 (3.57–11.91)  < 0.001 3.32 (1.04–10.61) 0.043
IRF score (high vs. low) 1585.65 (372.03–6758.19)  < 0.001 1855.25 (335.16–10,269.55)  < 0.001
  1. HR hazard ratio, CI confidence interval