Fig. 1

Single-cell transcriptome analysis reveals TEXscore distribution in NSCLC during targeted therapy. A t-SNE plots showing expression level of TEXscore in patients with NSCLC. B t-SNE plots showing cancer cells in patients with NSCLC colored by treatment time point (PD, PR/SD, and Pre). C Exosome-associated signature scores correlated with treatment time point PD during targeted therapy. The statistical difference of three gene clusters was evaluated using Kruskal–Wallis test. P values are indicated