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Table 4 Four modules from the PPI network with the criteria of MCODE score > 4 and number of nodes > 4

From: GSK2126458 has the potential to inhibit the proliferation of pancreatic cancer uncovered by bioinformatics analysis and pharmacological experiments

Cluster Score Nodes Edges Node IDs
1 19.128 40 373 IFITM1, IFI35, CXCL9, CXCL10, GBP2, FPR1, ANXA1, CCL19, CXCL13, NMU, C5AR1, GNAI1, GBP1, AGT, HLA-B, PSMB8, C3, SAMD9, SUCNR1, MX1, CXCL3, ISG15, IFITM3, IFIT1, OAS1, C3AR1, RSAD2, IFI6, IFI44, IFI27, CCL20, DDX60, MX2, CXCR4, UBE2L6, C5, XAF1, RNASEL, IFI44L, RTP4
2 12.062 33 193 ALB, EGF, HTR2B, VEGFC, CCKBR, PLOD2, HRH1, SERPINE1, EDNRA, PLAU, F8, SERPINH1, COL16A1, TIMP1, PLCB1, P4HB, PROS1, COL11A1, LGALS3BP, ISLR, COL4A1, COL4A2, COL10A1, COL8A1, FGG, TNC, FN1, COL5A1, CHRM3, SPARC, COL3A1, F2R, COL1A2
3 6.556 19 59 COMP, EREG, DLGAP5, TUBA1C, TOP2A, CTSE, LUM, TUBA4A, GMNN, FBN1, NDC80, THBS2, CKS2, CCNB1, ANLN, RND3, CEP55, CENPK, FAM83D
4 6.545 23 72 CD14, ITGB2, SDC1, IGFBP3, CD163, F3, CRP, MMP7, CD69, MMP1, C1orf162, PLAT, NCF2, CCL18, VSIG4, MMP9, CTSB, FCGR3B, FCER1G, C1QA, ALOX5AP, C1QB, IL18
  1. Score = Density*#Nodes