Table 3 The degree of connectivity of top 15 genes
Gene | Gene name | Degree of connectivity | Expression |
|---|---|---|---|
ALB | Albumin | 120 | Down-regulation |
EGF | Epidermal growth factor | 73 | Down-regulation |
MMP9 | Matrix metallopeptidase 9 | 53 | Up-regulation |
CXCL10 | C-X-C motif chemokine ligand 10 | 47 | Up-regulation |
TOP2A | Topoisomerase (DNA) II alpha | 46 | Up-regulation |
FN1 | Fibronectin 1 | 42 | Up-regulation |
CTSS | Cathepsin S | 40 | Up-regulation |
ACTB | Actin beta | 39 | Up-regulation |
ITGA2 | Integrin subunit alpha 2 | 38 | Up-regulation |
ISG15 | ISG15 ubiquitin-like modifier | 37 | Up-regulation |
CXCR4 | C-X-C motif chemokine receptor 4 | 37 | Up-regulation |
OAS1 | 2ʹ-5ʹ-Oligoadenylate synthetase 1 | 35 | Up-regulation |
COL3A1 | Collagen type III alpha 1 chain | 34 | Up-regulation |
FPR1 | Formyl peptide receptor 1 | 34 | Up-regulation |
ITGB2 | Integrin subunit beta 2 | 34 | Up-regulation |