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Table 3 The degree of connectivity of top 15 genes

From: GSK2126458 has the potential to inhibit the proliferation of pancreatic cancer uncovered by bioinformatics analysis and pharmacological experiments

Gene Gene name Degree of connectivity Expression
ALB Albumin 120 Down-regulation
EGF Epidermal growth factor 73 Down-regulation
MMP9 Matrix metallopeptidase 9 53 Up-regulation
CXCL10 C-X-C motif chemokine ligand 10 47 Up-regulation
TOP2A Topoisomerase (DNA) II alpha 46 Up-regulation
FN1 Fibronectin 1 42 Up-regulation
CTSS Cathepsin S 40 Up-regulation
ACTB Actin beta 39 Up-regulation
ITGA2 Integrin subunit alpha 2 38 Up-regulation
ISG15 ISG15 ubiquitin-like modifier 37 Up-regulation
CXCR4 C-X-C motif chemokine receptor 4 37 Up-regulation
OAS1 2ʹ-5ʹ-Oligoadenylate synthetase 1 35 Up-regulation
COL3A1 Collagen type III alpha 1 chain 34 Up-regulation
FPR1 Formyl peptide receptor 1 34 Up-regulation
ITGB2 Integrin subunit beta 2 34 Up-regulation