Fig. 8

Circ_0001361 silencing restrains in vivo xenograft tumor growth via regulating miR-525-5p/VMA21 axis. A Photographs illustrated tumors in xenografts. B Tumor volume at the indicated time points was shown. C Tumor weight from each group was presented. The expression of circ_0001361 (D), miR-525-5p (E), and VMA21 (F) in tumor tissues was detected by RT-qPCR. G Western blotting for VMA21 protein level in tumor tissues. All data are expressed as the means ± standard deviation from three independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001 versus the sh-NC group