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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Hsa_circ_0001361 facilitates the progress of lung adenocarcinoma cells via targeting miR-525-5p/VMA21 axis

Fig. 6

Overexpression of VMA21 reverses miR-525-5p-mediated anti-tumor effects on LUAD. A549 and PC9 cells were transfected with mimic NC or miR-525-5p mimics with or without vector or VMA21 plasmid. RT-qPCR (A) and Western blotting (B) for evaluating the levels of miR-525-5p and VMA21 in A549 and PC9 cells. C The growth of A549 and PC9 cells receiving multiple transfections was detected by MTT assay. D Colony formation assay for determining the oncogenicity of A549 and PC9 cells. E The migration ability was assessed by wound scratch assay. F Transwell assay for evaluating the invasion of A549 and PC9 cells. All data are expressed as the means ± standard deviation from three independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001 versus the indicated group

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