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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Transcriptomic analysis of tumor tissues and organoids reveals the crucial genes regulating the proliferation of lung adenocarcinoma

Fig. 7

Effects of CDK1, CCNB2, and CDC25A expression on the growth of LUAD organoids. a Two LUAD-derived organoids LUAD-1 and LUAD-2 were successfully constructed. b H&E staining of LUAD tissues and derived organoids. IHC analysis of CK5/CK6, CK7, and TTF1 expression in LUAD-1 and LUAD-2 organoids. c Expression of CDK1, CCNB2, and CDC25A in lung organoid and LUAD organoids by Western blot analysis. d By siRNA transfection, the expression of CDK1, CCNB2, and CDC25A was knocked down in LUAD-1 organoids. e, f The effects of CDK1, CCNB2, and CDC25A knockdown on the growth of LUAD organoids observed under a microscope (e) and using CCK-8 assays (f)

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Journal of Translational Medicine

ISSN: 1479-5876

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