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Table 4 Relationship between SLC7A11 or nuclear NRF2 expression and clinical response to CRT

From: SLC7A11 regulated by NRF2 modulates esophageal squamous cell carcinoma radiosensitivity by inhibiting ferroptosis

   Treatment response  
   CR + PR SD + PD P-value
Nuclear NRF2 Low expression (%) 49 (74.2) 17 (25.8) 0.002
High expression (%) 29 (47.5) 32 (52.5)  
SLC7A11 Low expression (%) 46 (70.8) 19 (29.2) 0.027
High expression (%) 32 (51.6) 30 (48.4)