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Table 3 Characteristics of patients with ESCC (n = 127)

From: SLC7A11 regulated by NRF2 modulates esophageal squamous cell carcinoma radiosensitivity by inhibiting ferroptosis

Variables NRF2 SLC7A11
Low (66) High (61) P-value Negative (65) Positive (62) P-value
Sex    0.189    0.728
 Male 38 42   40 40  
 Female 28 19   25 22  
Age    0.284    0.872
 ≤ 60 15 19   17 17  
 > 60 51 42   48 45  
Alcohol abuse    0.372    0.698
 Yes 22 25   23 24  
 No 44 36   42 38  
Smoking    0.803    0.665
 Yes 31 30   30 31  
 No 35 31   35 31  
Location    0.971    0.632
 Upper 29 27   30 26  
 Middle/lower 37 34   35 36  
Length, cm    0.035    0.623
 ≤ 4 35 21   27 29  
 > 4 31 40   38 33  
T stage    0.790    0.728
 T1–2 12 10   12 10  
 T3–4 54 51   53 52  
Lymph node metastasis    0.037    0.014
 N0–1 59 46   59 46  
 N2–3 7 15   6 16  
Metastasis    0.057    0.333
 M0 56 58   60 54  
 M1 10 3   5 8  
TNM stage    0.015    0.378
 I–II 22 9   18 13  
 III–IV 44 52   47 49