|
Maternal characteristics and biochemical variables
|
GDM (n = 21)
|
Control (n = 32)
|
P value
|
|---|
|
Age (years)
|
28.7 ± 3.42
|
31.5 ± 4.56
|
0.019*
|
|
Pre-BMI (kg/m2)
|
21.7 (19.96–23.47)
|
22.6 (18.95–25.25)
|
0.94
|
|
Gestational age (weeks)
|
25.3 (25–26)
|
25.6 (25–26)
|
0.32
|
|
Fasting glucose (mmol/L)
|
5.0 ± 0.43
|
4.7 ± 0.23
|
< 0.01**
|
|
1 h glucose (mmol/L)
|
9.15 (8.18–10.25)
|
7.35 (6.13–8.77)
|
< 0.01**
|
|
2 h glucose (mmol/L)
|
7.27 (6.51–8.08)
|
6.33 (5.77–7.29)
|
0.024*
|
|
Hb1AC (%)
|
5.01 (4.85–5.1)
|
4.84 (4.5–5.1)
|
0.091*
|
|
Fasting insulin (μU/L)
|
58.07 (40.1–66.4)
|
46.94 (32.45–47.58)
|
0.016*
|
|
1 h insulin (μU/L)
|
573.3 (301.6–728.4)
|
359.27 (198.1–480.2)
|
0.016*
|
|
2 h insulin (μU/L)
|
383.31 (183.1–574.8)
|
301.55 (199.2–368.0)
|
0.363
|
|
HOMA-IR
|
1.88 (1.25–2.25)
|
1.41 (0.91–1.43)
|
0.008**
|
|
Triglyceride (mmol/L)
|
2.31 ± 0.68
|
2.62 ± 0.82
|
0.171
|
|
Total cholesterol (mmol/L)
|
6.02 ± 1.14
|
6.11 ± 0.82
|
0.741
|
|
HDL (mmol/L)
|
1.86 ± 0.38
|
2.0 ± 0.39
|
0.199
|
|
LDL (mmol/L)
|
2.99 ± 0.79
|
2.97 ± 0.73
|
0.926
|
- Clinical characteristics, biochemical and hormonal variables of GDM and normoglycemic pregnant women at 24–28 weeks gestation are presented as mean ± SEM when normally distributed or median with 25–75th interquartile range when non-normal distributed. Statistically significant difference between the GDM and normoglycemic women group are highlighted (* P < 0.05, ** P < 0.01). HOMA-IR, HOMA-IR = FPG (mmol/L), FINS(μU/mL)/22.5
