Fig. 7

The relevance between the gut microbiota of genus level and the differential urinary metabolites. A and C: Spearman’s correlation heat map: red indicates positive correlation, while blue indicates negative correlation. The deeper color means the greater correlation (* P < 0.05, ** P < 0.01). B and D: The gut microbiota of genus level, predicted by metabolic variation (|r|> 0.4), is labeled with a similarity value. Lines connecting with metabolites show the direction of relevance to each genus of microbe with the red (positive) or blue (negative) lines