Fig. 9

External and experimental validation of COL5A2 and EPHB2 expression levels and independent prognostic value in LUAD patients. A Oncomine database showing the transcriptomic aberration of COL5A2 and EPHB2 in pancancer tissues. B, C The GEPIA database exhibiting the transcriptomic aberration of COL5A2 and EPHB2 in LUAD tissues and nontumor tissues. D, E IHC assay indicates the protein expression levels of COL5A2 and EPHB2 in LUAD tissues and nontumor tissues. F, G Kaplan–Meier Plotter database revealed the independent prognostic value of COL5A2 (F) and EPHB2 (G) in lung cancer patients. H, I TIMER database showing the correlation between immune cell infiltration and COL5A2 (H) and EPHB2 (I) in LUAD patients