Fig. 6

Comparison of the difference in the tumor microenvironment in high- and low-risk patients. A Heatmap showing the abundance of immune cell infiltration between high- and low-risk patients. B The radar chart shows the correlation with immune cell infiltration and the risk score of the angiogenic gene signature in LUAD patients. C–F The box plot indicates the abundance of infiltrating immune cells, including M0 macrophages (C), neutrophils (D), resting NK cells (E), and activated memory CD4 T cells (F), between high- and low-risk patients. G The heatmap revealed the expression level of immune checkpoints in the high-risk group and low-risk group. H The circle chart shows the relationship between the level of immune checkpoints and risk score in LUAD patients. I–L The box plot indicates the expression level of immune checkpoints, such as B7H3 (I), PD-1 (J), PDL-1 (K), and PDL-2 (L), in high-risk and low-risk patients