Fig. 5

Validation of the correlation with tumor mutation burden and risk score of angiogenesis-related signature in LUAD patients. A, B The waterfall plot shows the mutation landscape of the top 10 genes and two angiogenic genes in LUAD patients with low-risk scores (A) and high-risk scores (B). C, D The Sankey diagram and box plot indicate the correlation with tumor mutation burden and risk score in LUAD patients. E, F Kaplan–Meier (K-M) survival curves revealed the prognostic value of TMB with or without combination with the risk score in LUAD patients. G, H GSEA revealed the positive signaling pathway (G) and negative signaling pathway (H) in high-risk patients