Skip to main content
Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Different modulation effects of 1 Hz and 20 Hz transcutaneous auricular vagus nerve stimulation on the functional connectivity of the periaqueductal gray in patients with migraine

Fig. 2

vlPAG based connectivity results. A Compared to pre-taVNS resting-state, 1 Hz taVNS had significantly greater connectivity with the MCC, precuneus, Cuneus, and left MFG (not present in the figure). B Significant negative correlation was observed in migraine attacks and vlPAG-MCC connectivity in pre-taVNS resting-state preceding to the 1 Hz taVNS. Bonferroni correction was applied, and the significance threshold was adjusted to p < 0.0125 because four significant clusters were identified. C Compared to 20 Hz, 1 Hz taVNS had significant connectivity increases (stimulation minus pre-taVNS resting-state) with the MCC, precuneus, ACC, and left insula. FC functional connectivity, vlPAG ventrolateral periaqueductal gray, MCC middle cingulate cortex, PCu precuneus, MFG middle frontal gyrus, ACC anterior cingulate cortex, INS insula

Back to article page