Table 2 Univariate and multivariate analysis for pCR-score and important factors
Factors | Univariate analysis | Multivariate analysisa | Multivariate analysisb | |||
|---|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
pCR-score | 3.516 (2.003–6.173) | < 0.001 | – | – | 4.045 (1.822–8.980) | 0.001 |
Subtypes | – | < 0.001 | – | 0.003 | – | 0.084 |
 HR +/HER2- | 1 | 1 | 1 | 1 | 1 | 1 |
 HR +/HER2 +  | 8.939 (1.861–42.944) | 0.006 | 8.049 (1.484–43.664) | 0.016 | 2.899 (0.395–21.282) | 0.295 |
 HR-/HER2 − | 5.900 (1.041–33.477) | 0.045 | 4.798 (0.733–31.387) | 0.102 | 2.327 (0.262–20.671) | 0.449 |
 HR-/HER2 +  | 32.778 (7.031–152.815) | < 0.001 | 21.497 (4.089–113.00) | < 0.001 | 12.923 (1.783–93.638) | 0.011 |
sTILs density | – | 0.002 | – | 0.041 | – | 0.060 |
 Low | 1 | 1 | 1 | 1 | 1 | 1 |
 Moderate | 7.673 (2.302–25.581) | 0.001 | 5.374 (1.311–22.021) | 0.019 | 8.256 (1.404–48.546) | 0.020 |
 High | 14.250 (2.143–94.741) | 0.006 | 9.206 (0.939–90.247) | 0.057 | 7.379 (0.511–106.471) | 0.142 |
T stage | 0.754 (0.290–1.962) | 0.563 | 1.515 (0.428–5.356) | 0.519 | 2.219 (0.487–10.119) | 0.303 |
Ki67 | 4.571 (0.571–36.610) | 0.152 | 1.166 (0.116–11.737) | 0.897 | 1.859 (0.142–24.352) | 0.636 |
Nuclear grade | 1.987 (0.753–5.240) | 0.165 | 1.024 (0.283–3.708) | 0.971 | 1.076 (0.233–4.956) | 0.926 |