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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Fibroblast growth factor 11 (FGF11) promotes non-small cell lung cancer (NSCLC) progression by regulating hypoxia signaling pathway

Fig. 7

FGF11 knockdown inhibits NSCLC tumorigenesis in vivo. A549 and NCI-H460 cells were infected with FGF11 shRNA and FGF11 overexpression lentivirus. Cells were inoculated into balb/c nude mice (n = 5 mice/group). A The tumor growth curve in FGF11 shRNA and control group. B Tumor weight quantification in FGF11 shRNA and control group. C Immunohistochemistry (IHC) analysis of Ki-67 expression in FGF11 shRNA and control group. D The tumor growth curve in FGF11 overexpression and control group. E Tumor weight quantification in FGF11 overexpression and control group. F Immunohistochemistry (IHC) analysis of Ki-67 expression in FGF11 overexpression and control group. The results are represented as mean ± standard derivation. *P < 0.05, ** P < 0.01, ***P < 0.005 vs. control group

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