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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Fibroblast growth factor 11 (FGF11) promotes non-small cell lung cancer (NSCLC) progression by regulating hypoxia signaling pathway

Fig. 1

FGF11 is upregulated in human NSCLC tissues and is associated with poor prognosis. A The relative expression of FGF11 in GSE75037 dataset. B The relative expression of FGF11 in GSE81089 database. C qPCR analysis of FGF11 expression in 100 cases of NSCLC tissues and 30 cases of adjacent normal tissues. D The examination of FGF11 protein level by immunohistochemistry (IHC) in NSCLC tumor tissue and adjacent normal tissue. E Kaplan–Meier plotter survival analysis of 1144 cases of NSCLC patients from TCGA database. F Kaplan–Meier plotter analysis of survival probability of FGF11 high expression group (n = 50) and the low expression group (n = 50) in NSCLC patients. G qPCR analysis of FGF11 expression in NSCLC cell lines (A549, NCI-H460, CALU3, H1975) and human normal lung epithelial cell line (BEAS-2B). H Western bot analysis of FGF11 protein level in NSCLC cell lines (A549, NCI-H460, CALU3, H1975) and human normal lung epithelial cell line (BEAS-2B). The above data in (G and H) are the summary of the measurements of 3 independent experiments (mean ± standard deviation). *P < 0.05, ** P < 0.01, ***P < 0.001

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