Skip to main content

Table 1 The relationship between DDX27 expression and clinical pathology factors in 165 breast cancer patients

From: DEAD-box helicase 27 enhances stem cell-like properties with poor prognosis in breast cancer

Factors Number (%) DDX27 χ2 p-value Crude OR (95% CI)
Low (%) High (%)
Age     0.253 0.6149a  
 < 60 127 (76.97) 51 (30.91) 76 (46.06)    Reference
 ≥ 60 38 (23.03) 17 (10.30) 21 (12.73)   0.6151b 0.829 (0.399–1.722)
Tumor size     12.053 0.0005a  
 < 3 95 (57.58) 50 (30.30) 45 (27.27)    Reference
 ≥ 3 70 (42.42) 18 (10.91) 52 (31.52)   0.0007b 3.210 (1.642–6.276)
Lymph node status     11.334 0.0008a  
 Negative 109 (66.06) 55 (32.73) 54 (32.73)    Reference
 Positive 56 (33.94) 13 (7.88) 43 (26.06)   0.0010b 3.369 (1.631–6.957)
ER     3.137 0.0765a  
 Negative 54 (32.73) 17 (10.30) 37 (22.42)    Reference
 Positive 111 (67.27) 51 (30.91) 60 (36.36)   0.0783b 0.541 (0.272–1.072)
PR     1.203 0.2726a  
 Negative 54 (32.73) 19 (11.52) 35 (21.21)    Reference
 Positive 111 (67.27) 49 (29.70) 62 (37.58)   0.2737b 0.687 (0.351–1.346)
HER2     0.232 0.6298a  
 Negative 138 (83.64) 58 (35.15) 80 (48.48)    Reference
 Positive 27 (16.36) 10 (6.06) 17 (10.30)   0.6302b 1.232 (0.526–2.887)
Ki-67 index (%)     7.466 0.0063a  
 < 20 34 (20.61) 21 (12.73) 13 (7.88)    Reference
 ≥ 20 131 (79.39) 47 (28.48) 84 (50.91)   0.0076b 2.887 (1.326–6.288)
Molecular subtype     2.570 0.4628a  
 Luminal A 23 (13.94) 12 (7.27) 11 (6.67)    Reference
 Luminal B 81 (49.09) 35 (21.21) 46 (27.88)   0.4470b 1.434 (0.566–3.629)
 HER2 27 (16.36) 10 (6.06) 17 (10.30)   0.2845b 1.855 (0.598–5.748)
 TNBC 34 (20.61) 11 (6.67) 23 (13.94)   0.1377b 2.281 (0.768–6.776)
Histological grade     8.282 0.0040a  
 I–II 127 (76.97) 60 (36.36) 67 (40.61)    Reference
 III 38 (23.03) 8 (4.85) 30 (18.18)   0.0054b 3.358 (1.429–7.890)
TNM stage     23.606 < 0.0001a  
 I 37 (22.42) 28 (16.97) 9 (16.97)    Reference
 II 109 (66.06) 35 (21.21) 74 (44.85)   < 0.0001b 6.489 (2.767–15.217)
 III 19 (11.52) 5 (3.03) 14 (8.48)   0.0005b 9.333 (2.647–32.915)
  1. ap-value—came from Pearson Chi-square tests or Fisher’s exact test
  2. bp-value—came from Logistic regression analyses