Fig. 1

TRIM29 expression was upregulated and correlated with survival in pancreatic cancer. A GEPIA database analysis showed that the expression of TRIM29 was significantly increased in pancreatic cancer (PC) (*p < 0.05, T means tumour; N means normal). B and C, Determination of TRIM29 protein and mRNA levels in PC tissues and paired non-tumour tissues using western blotting and qRT-PCR. GAPDH was used as an internal control (** p < 0.01, N = Normal, T = Tumour). Representative images (D) and quantification (E) of TRIM29 IHC staining in 126 paired PC and non-cancer tissues collected in our center. A high TRIM29 expression was observed in 66.04% (77/126) (** p < 0.01) of samples. F, Kaplan–Meier survival curves revealed that the patients with high levels of TRIM29 expression exhibited a shorter overall and disease-free survival than those with lower levels