Fig. 3

Volcano plot (fold change and significance) of protein expression changes in different group sets. A All patients with psoriasis versus HC group, B PsO group versus HC group, C PsA group versus HC group, and D PsA group versus PsO group. The fold change of all group sets were all log² transformed and plotted against their -log¹⁰ transformed p-values. Each spot represents an identified protein. The threshold p = 0.05 is indicated as a horizontal line; the threshold of a ratio of fold change is indicated by vertical lines. The relationship of differentially expressed proteins in the PsA group versus PsO group was shown using E GeneMANIA and F STRING