Development and validation of a score to predict mortality in ICU patients with sepsis: a multicenter retrospective study

Table 4 Comparison of models in predicting the ICU mortality of sepsis

	Predictive model	AUC	P value	HL Chi-square	P value	IDI	P value
Midwest development cohort	POSMI	0.831 (0.813–0.850)		10.963	0.2038
	SOFA	0.728 (0.703–0.754)	< 0.001			0.102 (0.082–0.123)	< 0.001
	APACHE IV	0.773 (0.752–0.795)	< 0.001			0.081 (0.060–0.102)	< 0.001
West validation cohort	POSMI	0.829 (0.809–0.049)		3.0918	0.9285
	SOFA	0.741 (0.716–0.766)	< 0.001			0.108 (0.085–0.131)	< 0.001
	APACHE IV	0.763 (0.740–0.786)	< 0.001			0.095 (0.073–0.117)	< 0.001
South validation cohort	A-SIMP	0.825 (0.805–0.845)		10.888	0.2081
	SOFA	0.736 (0.740–0.786)	< 0.001			0.084 (0.062–0.105)	< 0.001
	APACH IV	0.758 (0.734–0.782)	< 0.001			0.077 (0.057–0.098)	< 0.001
Wenzhou validation cohort	POSMI	0.798 (0.769–0.826)		13.135	0.1073
	SOFA	0.747 (0.714–0.780)	0.005			0.042 (0.014–0.069)	0.003
	APACHE IV	0.777 (0.747–0.807)	0.208			0.035 (0.001–0.060)	0.007

AUC area under curve, IDI integrated discrimination improvement, HL Hosmer–Lemeshow

ISSN: 1479-5876