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Table 2 Risk factors for predictive model for ICU mortality in the midwest development cohort (n = 4236)

From: Development and validation of a score to predict mortality in ICU patients with sepsis: a multicenter retrospective study

Variable β OR (95%CI)a P-value Pointb
Age, years     
 ≥ 50 to < 60 0.7901 2.203 (1.294–3.899) 0.005 2
 ≥ 60 to < 75 1.0021 2.724 (1.641–4.724)  < 0.001 2.5
 ≥ 75 1.2261 3.407 (2.050–5.923)  < 0.001 3
Temperature < 37 °C 0.7332 2.081 (1.546–2.811)  < 0.001 2
Respiratory rate, breaths/min    
 ≥ 30 to < 35 0.6111 1.842 (1.312–2.600)  < 0.001 1.5
 ≥ 35 0.5886 1.801 (1.292–2.526)  < 0.001 1.5
 MAP ≤ 50, mmHg 0.8744 2.397 (1.673–3.481)  < 0.001 2
 SpO2 < 90% 0.9508 2.587 (1.926–3.502)  < 0.001 2
 Ventilation 1.2014 3.325 (2.665–4.156)  < 0.001 3
 Albumin < 2, g/dL 0.6289 1.875 (1.343–2.639)  < 0.001 1.5
Bilirubin, mg/dL     
 ≥ 0.8 to < 1.4 0.5366 1.710 (1.202–2.456) 0.003 1
 ≥ 1.4 0.7915 2.206 (1.559–3.158)  < 0.001 2
Lactate, mmol/L     
 ≥ 2.5 to < 4.2 0.4558 1.577 (1.117–2.241) 0.010 1
 ≥ 4.2 0.9476 2.579 (1.869–3.595)  < 0.001 2
BUN, mg/dL     
 ≥ 21 to < 33 0.4779 1.612 (1.117–2.349) 0.012 1
 ≥ 33 to < 52 0.4119 1.509 (1.049–2.192) 0.028 1
 ≥ 52 1.0401 2.829 (2.006–4.043)  < 0.001 2.5
Hepatic failure 1.0094 2.744 (1.468–4.993) 0.001 2.5
Metastatic cancer 0.5894 1.802 (1.051–2.997) 0.027 1
Total score     0–25
  1. OR odds ratio
  2. aICU mortality odds ratio
  3. bAssignment of points to risk factors was based on a linear transformation of the corresponding β regression coefficient. The coefficient of each variable was divided by 0.4119 (the smallest absolute β value, corresponding to BUN ≥ 33 to < 52, mg/dL) and allocated an integer or an half integer score for each variable