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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Immune and stromal scoring system associated with tumor microenvironment and prognosis: a gene-based multi-cancer analysis

Fig. 4

The TME subtype was associated with TME cellular infiltration, functional markers and communication networks. a The patterns of cellular infiltration of TME subtypes in TCGA LUAD (n = 501). b The patterns of cellular infiltration of TME subtypes in TCGA SKCM (n = 352). c The patterns of cellular infiltration of TME subtypes in TCGA HNSC (n = 514). d The ratios of co-inhibitory/co-stimulatory molecules (PD-1 + CTLA4 + LAG3 + TIM-3) / (CD28 + CD40LG) of TME subtypes in TCGA LUAD (n = 501). e The ratios of co-inhibitory/co-stimulatory molecules of TME subtypes in TCGA SKCM (n = 352). f The ratios of co-inhibitory/co-stimulatory molecules of TME subtypes in TCGA HNSC (n = 514). g TME communication networks of different TME subtypes in the training datasets. LUAD, lung adenocarcinoma; SKCM, skin cutaneous melanoma; HNSC, head and neck squamous cell carcinoma; TME, tumor microenvironment; HH, immunehigh stromalhigh; HL, immunehigh stromallow; LH, immunelow stromalhigh; LL, immunelow stromallow

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