Fig. 6

The survival data of pancreatic patients with or without genetic alterations in m6A regulators (cBioPortal). A Kaplan–Meier plots comparing the disease -free survival (DFS) in pancreatic cancer patients with or without genetic alterations of m6A regulators (log-rank test, P = 0.035). Genetic alterations in m6A regulators were associated with poorer DFS in pancreatic cancer patients. B Kaplan–Meier plots compared overall survival (OS) in pancreatic cancer patients with or without genetic alterations in m6A regulators (log-rank test, P = 0.007). Genetic alterations in m6A regulators were associated with poorer OS in pancreatic cancer patients. C, D A Kaplan–Meier plot and log-rank test analyzed the survival data of 177 patients with pancreatic cancer in the Cancer Genome Atlas (TCGA). We selected m6A regulators with genetic alterations showing statistically significant effects on pancreatic cancer patient survival (P < 0.05). Column bar graphs display the hazard ratio (HR) of DFS/PFS and OS of pancreatic cancer patients with genetic alterations in selected m6A regulators. Red represents HR > 1, and blue represents HR ≤ 1