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Table 4 Correlation between exosome AEBP1 level and clinical parameters in DKD patients

From: Extracellular vesicle-derived AEBP1 mRNA as a novel candidate biomarker for diabetic kidney disease

Clinical parameters Exosome AEBP1 level
R value P value
Age (yrs) − 0.283 0.307
BMI − 0.242 0.384
SBP (mmHg) − 0.309 0.263
DBP (mmHg) − 0.140 0.619
HbA1c (%) − 0.062 0.827
eGFR (MDRD, ml/min/1.73m2) − 0.614 0.0015
eGFR (CKD-EPI, ml/min/1.73m2) − 0.59 0.020
BUN (mmol/L) 0.298 0.280
Creatinine (µmol/L) 0.629 0.012
TC (mmol/L) − 0.170 0.545
TG (mmol) − 0.161 0.567
LDL (mmol/L) − 0.556 0.031
HDL (mmol/L) − 0.034 0.905
24-h urine protein (g/d) 0.559 0.0304
Urine protein to creatinine ratio − 0.079 0.778
Albumin (g/L) − 0.335 0.222
Albumin/creatinine ratio (mg/g) 0.258 0.374
Urine β2MG (mg/L) − 0.003 0.993
Urine RBP (mg/L) 0.357 0.255
Urine CYC (mg/L) − 0.189 0.667
Serum CYC (mg/L) 0.656 0.008
Hemoglobin (g/L) − 0.424 0.116
WBC (109/L) − 0.101 0.719
Monocytes (109/L) − 0.068 0.810
Lymphocytes (109/L) − 0.157 0.576
Neutrophils (109/L) − 0.041 0.885
hsCRP (mg/L) 0.474 0.074
  1. Bold indicates p < 0.05
  2. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, T2DM type II diabetes mellitus, HbA1c glycated hemoglobin, MDRD The Modification of Diet in Renal Disease, CKD-EPI The Chronic Kidney Disease Epidemiology Collaboration, TC total cholesterol, TG triglycerides, HDL high density lipoprotein, LDL low-density lipoprotein cholesterol, BUN blood urea nitrogen, RBP retinol-binding protein, CYC cystatin-C, WBC White Blood Cell