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Table 4 Correlation between exosome AEBP1 level and clinical parameters in DKD patients

From: Extracellular vesicle-derived AEBP1 mRNA as a novel candidate biomarker for diabetic kidney disease

Clinical parameters

Exosome AEBP1 level

R value

P value

Age (yrs)

− 0.283

0.307

BMI

− 0.242

0.384

SBP (mmHg)

− 0.309

0.263

DBP (mmHg)

− 0.140

0.619

HbA1c (%)

− 0.062

0.827

eGFR (MDRD, ml/min/1.73m2)

− 0.614

0.0015

eGFR (CKD-EPI, ml/min/1.73m2)

− 0.59

0.020

BUN (mmol/L)

0.298

0.280

Creatinine (µmol/L)

0.629

0.012

TC (mmol/L)

− 0.170

0.545

TG (mmol)

− 0.161

0.567

LDL (mmol/L)

− 0.556

0.031

HDL (mmol/L)

− 0.034

0.905

24-h urine protein (g/d)

0.559

0.0304

Urine protein to creatinine ratio

− 0.079

0.778

Albumin (g/L)

− 0.335

0.222

Albumin/creatinine ratio (mg/g)

0.258

0.374

Urine β2MG (mg/L)

− 0.003

0.993

Urine RBP (mg/L)

0.357

0.255

Urine CYC (mg/L)

− 0.189

0.667

Serum CYC (mg/L)

0.656

0.008

Hemoglobin (g/L)

− 0.424

0.116

WBC (109/L)

− 0.101

0.719

Monocytes (109/L)

− 0.068

0.810

Lymphocytes (109/L)

− 0.157

0.576

Neutrophils (109/L)

− 0.041

0.885

hsCRP (mg/L)

0.474

0.074

  1. Bold indicates p < 0.05
  2. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, T2DM type II diabetes mellitus, HbA1c glycated hemoglobin, MDRD The Modification of Diet in Renal Disease, CKD-EPI The Chronic Kidney Disease Epidemiology Collaboration, TC total cholesterol, TG triglycerides, HDL high density lipoprotein, LDL low-density lipoprotein cholesterol, BUN blood urea nitrogen, RBP retinol-binding protein, CYC cystatin-C, WBC White Blood Cell