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Table 1 Clinical characteristics of patients and newborns in the validation cohort

From: Extracellular vesicle-associated miRNAs are an adaptive response to gestational diabetes mellitus

 

NGT (n = 14)

GDM (n = 8)

p values

Maternal baseline characteristics

 Age (years)

31.6 ± 5.24

36.9 ± 3.02

0.003

 Race

  

0.256

 Chinese

1 (5.56%)

0

 

 European

8 (44.4%)

8 (88.9%)

 

 Indian–Pakistan

3 (16.7%)

0

 

 Latin–American

5 (27.8%)

1 (11.1%)

 

 Philipina

1 (5.56&)

0

 

 Height (cms)

162 ± 6.13

162 ± 3.52

0.929

 Pre-gestational weight (kg)

66.6 ± 13.9

61.7 ± 13.7

0.398

 Pre-gestational BMI

25.3 ± 4.67

23.5 ± 5.46

0.411

Screening and diagnostic results

 Gestational age O´Sullivan test

23.6 ± 3.6

24.4 ± 1.25

0.52

 O’Sullivan test result (mmol/L)

7.0 ± 1.67

9.70 ± 1.88

0.004

 Gestational age at OGTT

26.4 ± 0.55

26.0 ± 0.75

0.266

 Fasting OGTT (mmol/L)

4.38 ± 0.25

4.58 ± 0.53

0.342

 1 h OGTT (mmol/L)

8.22 ± 1.16

11.1 ± 1.15

 < 0.001

 2 h OGTT (mmol/L)

6.64 ± 2.14

10.0 ± 1.45

0.005

 3 h OGTT (mmol/L)

5.21 ± 2.01

7.79 ± 1.50

0.016

Delivery data

 Gestational age at delivery (weeks)

39.6 ± 1.2

39.1 (± 1.22)

0.298

 Fetal sex (male/female)

11/7

3/6

0.236

 Birthweight (grams)

3480 ± 148

3154 ± 100

0.208

 Birthweight percentile

47.8 ± 31.4

43.2 (± 25.1)

0.684

Route of delivery

0.363

 Cesarean

6 (33.3%)

1 (11.1%)

 

 Vaginal

12 (66.7%)

8 (88.9%)

 
  1. Data are presented as mean ± SD. All pregnancies were normotensive, and without intrauterine infection or any other medical or obstetrical complications except GDM. In race and route of delivery, (%) is the percentage of the total